CAVT
Computer Assisted Vacuum Thrombectomy (CAVT™) is revolutionizing frontline interventional clot removal designed for speed, safety, and simplicity.
What is CAVT?
Computer Assisted Vacuum Thrombectomy (CAVT) is an advanced, minimally invasive procedure used to remove thrombus from veins and arteries, and for the treatment of pulmonary embolism (PE).
This technology leverages the power of microprocessors equipped with clot detection algorithms. These intelligent algorithms are designed to facilitate rapid recognition and removal of blood clots.
CAVT offers a more powerful and advanced alternative to analog methods such as open surgery, large-bore aspiration thrombectomy (LBAT), and catheter-directed thrombolysis (CDT).
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Advancing Endovascular Care with Cutting-Edge Software
The core feature of CAVT technology is its refined algorithms, which detect the difference between thrombus and patent flow. These algorithms work together to automatically adjust the vacuum provided by the Penumbra ENGINE®.
The system seamlessly alternates between “Sampling Mode” and “Clot Detected Mode,” and provides physicians with audio-visual cues for a more intuitive experience.
This distinction allows for an immediate and clear response to the changing dynamics of the procedure, designed to minimize the risk of complications and optimize thrombus removal.
Lightning Bolt® CAVT hardware
The Impact of CAVT1, a
Research shows that PE patients treated with CAVT experience shorter hospital stays and fewer complications compared to other treatment options. Including:
Shorter total hospital length of stay
25% - 35%
(statistically significant relative to all other modalities studied)
Lower composite complicationsb
3.4x
(statistically significant relative to other mechanical thrombectomy)
Higher rate of patients discharged to home
25% - 30%
(statistically significant relative to all other modalities studied)
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Learn more about CAVT and its positive impact on hospital resource utilization in PE treatment
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Images used with permission and provided for illustrative purposes only. Procedural techniques and decisions based on physician’s medical judgment. Individual results may vary. Consents on file at Penumbra, Inc.
Benefits of CAVT
Speed
CAVT microprocessors can automatically initiate Modulated Aspiration when faced with tough thrombus, allowing the system to ingest clot faster and rapidly restore blood flow.
Safety
Penumbra’s MaxID aspiration catheters are designed to have atraumatic and trackable profiles engineered to navigate delicate arteries, veins, and the complex pulmonary vasculature.
Simplicity
Penumbra’s CAVT portfolio streamlines and simplifies clot removal through intraprocedural audio-visual cues, and the ability to address a wide range of peripheral vessels.
CAVT Products
Penumbra’s CAVT platform harnesses advanced computer technology designed to enable rapid restoration of blood flow in cases such as acute limb ischemia, venous thrombus, and pulmonary embolism. The platform utilizes the Penumbra ENGINE Aspiration Source, which delivers nearly pure, continuous vacuum (-29 inHg or -98.2 kPa) to our catheters, enabling effective thrombus removal in a wide range of vessel sizes.
a. Retrospective analysis derived from Vizient Clinical Data Base, based off 2,060 1:1 propensity score matched intermediate-risk PE patients divided into 4 equally proportional groups
b. Composite complications is defined by Vizient and in this study includes: In Hospital Stroke, GI Hemorrhage Prevention, Post Operative Infection, Hospital Acquired AMI, Readmit for Infection Due to Previous Care, Readmit for other complications of internal device/Implant/Graph, Readmit for Other Surgical Wound Complications, Infection/Inflammation Due to Internal Device/Implant/Graph, Post Operative Shock, Aspiration/Pneumonia, C-Diff.
1. Patel P, Dohad S, Moriarty J, et al. Healthcare resource utilization and outcomes among patients with intermediate-risk pulmonary embolism treated with computer-assisted vacuum thrombectomy versus other treatment modalities. Presented at: VIVA (Vascular InterVentional Advances) 2024; 04 November 2024; Las Vegas, NV.
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Contact us to learn more about CAVT and schedule a demo